Pritam Ganguly

Assistant Project Scientist
Shea Research Group

Contact Phone

(805) 893-2767

Office Location

3606 PSB-N

Research

I study the effects of cosolvents on proteins. We are interested in understanding the effects of cellular components on the conformational stability and aggregation propensities of intrisically disordered proteins (IDPs). I have particular interest in the behavior of the IDP tau protein, associated with the pathology of Alzheimer's disease.

Publications

Catalytic Cross Talk Between Key Peptide Fragments that Couple Alzheimer's Disease with Amyotrophic Lateral Sclerosis

Laos, V.; Bishop, D., Ganguly; Schonfeld, G.; Trapp, B.; Lazar Cantrell, K.; Buratto, S.; Shea, J.-E.; Bowers, M. J. Am. Chem. Soc. 2021, 143 (9), 3494-3502

 

Terminal capping of an amyloidogenic Tau fragment modulates its fibrillation propensity

Arya, S.; Ganguly, P.; Arsiccio, A.; Claud, S. L.; Trapp, B.; Schonfeld, G. E.; Liu, X.; Lazar Cantrell, K. L.; Shea, J.-E.; Bowers, M. T. J. Phys. Chem. B 2020, 124 (40), 8772-8783.