The Department maintains an impressive collection of Mass Spectrometry, NMR Spectroscopy, Optical Characterization and X-Ray facilities.
The Department of Chemistry and Biochemistry operates an in-house Mass Spectrometry facility to support research and teaching activities. Mass Spectrometry is a primary tool for structure elucidation, molecular weight determination and molecular formula confirmation for organic and biological materials. This family of techniques measures the masses of organic and biological molecules by creating gas phase ions from the analytes and manipulating those ions in electric and magnetic fields. Chemical structure may be probed by fragmenting molecular ions and mass measuring the resulting product ions.
A wide range of ionization techniques and capabilities are available. Services are available by sample submission to the facility staff or by direct instrument access for trained users on a 24/7 basis. Facility staff is available for operator training as well as consultation on experimental design and data interpretation.
A Bruker Microflex LRF MALDI TOF mass spectrometer is used for the analysis of a broad range of compounds including small molecules, peptides, proteins, nucleic acids, and synthetic polymers. The Microflex LRF has a mass range of up to 20,000 Da in reflectron mode or up to 500,000 in linear mode. Additionally the instrument is capable of mass spectral imaging and post source decay analysis. Software is available for the analysis of polymer data.
A Waters GCT Premier Time-of-Flight MS is equipped with electron ionization (EI), chemical ionization (CI), and field ionization/field desorption (FI/FD) ion sources. EI, CI, and FI techniques are suitable for volatile and semi-volatile organic compounds with sample introduction via an Agilent capillary GC or by direct insertion probe for thermally labile compounds. FD is a powerful tool for the analysis of small polymers and other non-polar materials (<4000 Da). Full scan analyses and accurate mass measurement are available.
An HP GC/MSD is a dedicated GC-EI MS low resolution instrument for routine GC/MS analyses of volatile and semi-volatile organic compounds including reaction mixtures.
NMR spectroscopy is a highly sensitive technique in probing molecular structure and dynamics of chemical compounds, polymers and biomolecules. The in-house NMR Facility is currently home to four solution-state NMR spectrometers: Varian 400, 500, and 600 MHz spectrometers and a Bruker 800 MHz spectrometer. All spectrometers are equipped with multiple solution-state NMR probes for direct or indirect detection of 1H/19F and low frequency nuclei such as 13C, 31P, and 15N. The 600 and 800 MHz spectrometers are also each equipped with a cryoprobe. The state-of-the-art, cryogenically cooled probes provide significantly enhanced 1H and/or 13C sensitivity relative to room temperature probes, reducing experiment time up to 20 fold and making it possible for the detection of small-quantity of material. The high-field spectrometers along with the cryoprobes are ideal for biomolecular protein NMR. They are also being used for challenging small molecule projects, such as studies of low-quantity of natural products. The 400 and 500 MHz NMR spectrometers are dedicated to the needs of the synthetic chemists. Experiments conducted at the Facility range from routine 1D and 2D experiments for small molecule and polymer analysis at natural abundance to complex 3D and 4D multinuclear correlated experiments for protein structure determination using isotope-labeled samples. All instruments are user-operated and are open to researchers with 24/7 access after proper training. User training is offered throughout the year in group and mostly hands-on individual sessions. Technical assistance is readily available in data collection and analysis.
The NMR user lab of the Department of Chemistry and Biochemistry collaborates with the Spectroscopy Facility of the Materials Research Laboratory (MRL), operated by Dr. Jerry Hu. The MRL-supported NMR facility is also available to all users on campus, and offers complementary capabilities, including solid state NMR instrumentation at 300 and 500 MHz, solution NMR instrumentation at 500 and 600 MHz, a CW Electron Paramagnetic Resonance (EPR) spectrometer and NMR imaging and diffusometry instrumentation. The laboratory of Prof. Han offers other dedicated capabilities, including pulsed EPR and dynamic nuclear polarization NMR at 10 and 200 GHz.
Facility Manager and Spectroscopist: Dr. Hongjun Zhou; firstname.lastname@example.org
Location: Physical Sciences Building North (PSBN), Room 3614A
Wepage: NMR Facility
In the Optical Characterization Facility, light is used to probe the intrinsic properties of materials prepared by chemists and serves as an analytical and quality control tool. We study energy and charge migration in materials for novel optoelectronic devices, test new biosensors and materials for data storage, zap bacteria with laser beams, and provide state of the art technical capabilities that are not commonly available to non-expert chemists in their own laboratory. The optical characterization facility gives students the ability to have hands-on experience in modern optical spectroscopy. The facility does not have dedicated instruments; rather experiments are designed to meet the need of the user. The facility manager assists its users in the design, assembly, and final analysis of experimental data. Custom optical experiments and support include photoconductive atomic force microscope, solar simulators for photovoltaics research or optical setups for characterization of organic semiconductors and many more chemical, materials and biological systems.
Major Capabilities and Areas of Expertise:
Time-resolved fluorescence measurements in the range 50 ps – 10 s (time-correlated single-photon counting etc.).
Transient absorption spectroscopy with sub-100 fs resolution
Custom luminescence spectroscopy (temperature-dependence, photoluminescence up-conversion, thermoluminescnce, electroluminescence, quantum-yield measurements)
Non-linear optical spectroscopy (multiphoton absorption and optical harmonics spectroscopy)
Raman spectroscopy and microscopy
High laser power processing of materials
Facility Instrumentation include 1 kHz repetition rate, 100 fs pulse Ti:Sapphire amplifier, Ti:Sapphire femtosecond oscillator laser, optical harmonics generator, high power Ar-ion laser with single-mode operation capability, various smaller semiconductor and gas lasers. We also have several monochromators equipped with spectroscopic CCD cameras, single channel detectors and a high-end Raman microscope.
The in-house X-ray facility allows for single crystal x-ray structure determination for researchers in the Department of Chemistry and Biochemistry, as well as UCSB wide. There are three instruments currently housed in the facility. A fine focus sealed tube Mo source better for small molecule structure determination, a rotating anode Cu source used mainly for protein crystallography and other biologically relevant samples, and a sealed tube Cu source for 2-D powder diffraction. Three instrumentations are available:
The Kappa APEX II diffractometer has a fine focus sealed tube Mo x-ray source combined with a Bruker 4 axis diffractometer an APEX II detector and an Oxford Cryostream-Plus low temperature device
The Proteum diffractometer is equipped with a Microstar rotating Cu anode x-ray source and a 3 axis platform diffractometer, alongside a Proteum detector and an Oxford 700 Cryostream low temperature device
The Powder diffractometer is a Scintag X2 with a sealed Cu tube x-ray source and a solid-state point detector
Faculty and students also have access to the complementary MRL X-ray facility, located just a few steps from the chemsitry building (http://www.mrl.ucsb.edu/mrl/centralfacilities/xray/index.html) ).
Facility Manager and Crystallographer: Dr. Guang Wu; email@example.com
Location: Physical Sciences Building North (PSBN), Room 4608
Webpage: X-ray Facility
- Low Temperature Single Crystal Data collection: $200.00/sample
- Low Temperature Single Crystal Data collection and Structure Determination: $252.00/sample
- Room Temperature Single Crystal Data collection: $150.00/sample
- Room Temperature Single Crystal Data collection and Structure Determination: $202.00/sample
- Single Crystal Cell Determination:$30.00/sample
- Other Special Service: Rate depending on the nature of the experiment and measurement time
The Department maintains full-service machine and glass shops for making custom items needed for cutting edge research. We also have a modern Computational Chemistry and Molecular Modeling Laboratory which features 25 Dell Linux workstations. In order to make needed supplies readily available, the department also operates complete undergraduate and research storerooms.
The Department of Chemistry and Biochemistry maintains a full time and in-house glass blowing facility to benefit the research community and the graduate students. The glass shop provides consultation, fabrication and repair of scientific glassware for research and instruction. It is always open for anyone to come and discuss or design work projects. Repairs are fast and easy with Richard’s help. Key strengths of the services are custom design and construction, competitive cost on specialty items, the construction of high quality glass and no limits put to creative ideas.
Facility Manager and Glassblower: Richard Bock; firstname.lastname@example.org
Location: Chemistry 1520 (inside the Machine Shop)
The Chemistry and Biochemistry Department machine shop is an in house source for design and fabrication of specialty research equipment as well as repair and modification of almost all hardware used in the scientific environment. With over 50 years of combined experience in the machining and fabrication field, most of those in the academic research environment, the shop staff provides innovative solutions to problems and prompt service. Materials including stainless steel, aluminum, mild steel, brass, copper, machinable ceramics, heat resistant metals such as hastelloy, and plastics are commonly used for the work performed in the shop. A full service wood shop is also on site for any and all wood projects from custom office furniture to high quality and custom shelving and bookcases.
The Computer Support team manages the departmental email, web and file services, an instructional computing facility, as well the networks in Physical Sciences North and Chemistry buildings. Our team provides network connections (wired and wireless) and desktop support services to the department to support instructional and research activities. Additional computing support is available by recharge for more involved work - computer setup, virus cleanup, software configuration, interfacing with instruments, scripting, research computing etc.
Webpage: Computer Support
The teaching and research storeroom is an important in-house resource that assists the undergraduate teaching laboratories, supervises student workers and organizes and supervises the weekly preparation of chemicals, supplies and equipment. The storeroom managers guide faculty, staff and students in the safe handling of chemicals and teach appropriate safety measure for preventing accidents and health hazards in the laboratory. The storeroom managers also assist the testing and developments of new experiments for the teaching laboratories, as well as supply the graduate research laboratories.
Undergraduate Labs and Storeroom Managers: Elaine Merza and Lisa Stamper
Location: Physical Science Building (PSB) North 1642
The Department of Chemistry and Biochemistry offers a full suite of purchasing and shipping and receiving services, located in rooms 1225 and 1432 in the Chemistry building.
Research Storeroom Manager: Cabe Fletcher
Location: Chemistry 1432
Location: Chemistry 1225
The departmental administration includes the management of department finances, payroll, grants and contracts, travel and supply reimbursement and academic personnel administration. The department administration staff includes a team of eight admin staff members. The department MSO, financial manager, contract and grant analysts, payroll, recharge services and travel assistants, and an academic personnel analyst, as well as work study students. The department administration staff serves as a vital network of support to the Chemistry and Biochemistry, faculty, graduate and undergraduate students, researchers, visitors and staff. The administrative staff is responsible for all aspects of the academic and business management and the successful academic and business operations of the department.
Chemistry MSO: Katie Wright
Location: Room 1007, Building 232
Administrative Directory: Building 232
The Student Affairs (SA) team, including the SA Manager/Grad Advisor, Undergraduate Advisor, SA Program Assistant and SA Assistant/Peer Advisor(s) are responsible for the operation, support, and development of all departmental student-targeted programs. Creation and organization of quarterly course schedules (including faculty and teaching assistant schedules), graduate application processing, graduate recruitment event planning, annual student award administration, general administrative course support services, and future program development are managed by Student Affairs. Staff Advisors are the first and primary point of contact for all Chemistry and Biochemistry students in need of academic advising. In addition, Student Affairs provides administrative assistance for graduate and undergraduate students, including processing of petitions, progress checks, personal counseling and referral, career resource guidance, and enrollment and waiting list information.
Student Affairs Manager: India Madden
Location: Room 1001, Building 232